current members
people(home)

Principle Investigator
Anna Marie Pyle

Group II Intron
Olga Fedorova
Kevin Keating
Ifeoma Nwigwe
Michael Roitzsch
Amanda Solem
Navtej Toor
Nora Zingler

Helicase
Rudy Beran
Steve Ding
Andrew Kohlway
Chris Matranga
Victor Serebrov
Sean Taylor
Adriana Vela

Other Important people
Amelia Johnson
Gabriele Drews
Marcia McCleese





    Dr. Anna Marie Pyle  Principal Investigator
anna.pyle@yale.edu

Anna Marie Pyle
Biographical Information: Dr. Pyle became Professor of Molecular Biophysics and Biochemistry at Yale University in 2002. Prior to that, she was Professor of Biochemistry and Molecular Biophysics at Columbia University. Dr. Pyle has been named a Searle Scholar, a Beckman Young Investigator, an NSF National Young Investigator and an Irma T. Hirschl Career Scholar. Prior to joining the Columbia faculty in 1992, Dr. Pyle was a postdoctoral fellow in the laboratory of Thomas R. Cech at the University of Colorado. She received her Ph.D. in Chemistry under the direction of Jacqueline K. Barton at Columbia University.

Research Summary: Dr. Pyle uses the group II intron as a model system for studying ribozyme catalysis, RNA folding, and RNA-protein interactions. She also studies the mechanisms of RNA helicase enzymes, which are molecular motors that unwind RNA and displace proteins from RNA binding sites. This work is complemented by the development of new computational approaches for analyzing the chemical and structural properties of RNA.

Read Anna's CV
Read Anna's HHMI Profile



266 Whitney Avenue;
Room 334A Bass Building
Yale University
New Haven, CT 06511

Phone: 203-436-4047 (Bass 334A)
        : 203-432-6370 (Bass 331)
        : 203-432-8346 (Bass 333)
FAX: 203-432-5316

Web Master:
Kevin Keating
Last modified:
  19-Nov-2008