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2007 publications
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"A kinetic intermediate that regulates proper folding of a group II intron RNA", Christina Waldsich and Anna Marie Pyle, J. Mol. Biol. (2007) 375, 572-580.
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"Three essential and conserved regions of a group II intron are proximal to the 5’-splice site", Alexandre de Lencastre and Anna Marie Pyle, RNA (2007) 14, 11-24.
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"The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate", Rudolf K. Beran, Victor Serebrov and Anna Marie Pyle, J. Biol. Chem. (2007) 282, 34913-34920.
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"Evaulating and learning from RNA pseudotorsional space: Quantitative validation of a reduced representation for RNA structure", Leven M. Wadley, Kevin S. Keating, Chuck M. Duarte and Anna Marie Pyle, J. Mol. Biol. (2007) 372, 942-957.
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"The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication", Brett D. Lindenbach, B.M. Pragai, R. Montserret, Rudolf K. Beran, Anna Marie Pyle, F. Penin, and C.M. Rice S., J. Virol. (2007) 81, 8905-8918.
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"Spring-loaded mechanism of DNA unwinding by hepatitis C virus NS3 helicase", S. Myong, Michael M. Bruno, Anna Marie Pyle, and T. Ha, Science (2007) 317, 513-516.
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"Tinkering with transcription factor proteins: the role of transcription factor adaptation in developmental evolution", Günter P. Wagner and Anna Marie Pyle, Novartis Found.Symp. (2007) 284, 116-125; discussion 125-129, 158-163.
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"Folding of group II introns: a model system for large, multidomain RNAs?", Anna Marie Pyle, Olga Fedorova and Christina Waldsich, Trends Biochem Sci. (2007) 32, 138-145.
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"Calculation of pK(a)s in RNA: On the structural origins and functional roles of protonated nucleotides", Chris.L. Tang, Emil Alexov, Anna Marie Pyle and Barry Honig, J Mol Biol. (2007) 366, 1475-1496.
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"Group II intron folding under near-physiological conditions: collapsing to the near-native state", Olga Fedorova, Christina Waldsich and Anna Marie Pyle, J. Mol. Biol. (2007) 366, 1099-1114.
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"Alternative roles for metal ions in enzyme catalysis and the implications for ribozyme chemistry", Roland K.O. Sigel and Anna Marie Pyle, Chemical Reviews (2007) 107, 97-113.
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"A folding control element for tertiary collapse of a group II intron ribozyme", Christina Waldsich and Anna Marie Pyle, Nature Structural & Molecular Biology (2007) 14, 37-44.
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